INDICATORS ON KETAMINE ORAL DOSE FOR PAIN YOU SHOULD KNOW

Metabolism Ketamine is metabolized by using N-dealkylation towards the Lively metabolite norketamine principally by CYP2B6 and CYP3A4 also to a lesser extent by other CYP enzymes. Norketamine undergoes hydroxylation on the cyclohexone ring to kind hydroxynorketamine compounds by way of CYP-dependent pathways, which are conjugated with glucuronic ac